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+6017-8786220, +03-55245543
+6017-8786220, +03-55245543
Vitamin K3 is a synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo. It induces apoptosis in various cultured cells including leukemia cells. It has been shown that vitamin K exerts anti-tumor activity by inhibiting cdk1 activity and over expressing the c-myc gene to induce apoptotic cell death. Another hypothesis based on investigation done on the mode of actions of vitamin K suggests that VK3 induces apoptosis by promoting the generation of intracellular reactive oxygen intermediates and Fas/APO-1 expression.
| Properties | |
| Molecular Weight | 172.18 |
| Physical Description | White crystal or crystalline powder, almost odorless, hygroscopic, discolored in light. Soluble in water, slightly soluble in ethanol, insoluble in ether and benzene. |
| Purity | >98% |
| Storage Condition | Room Temperature |
| Molecular Formula | C11H8O2 |
